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In the presence of the mTOR inhibitor rapamycin, the effects of polyphyllin II on p-mTOR decrease and LC3B-II increase in colorectal cancer cells further confirmed polyphyllin II realizing autophagy via Akt/mTOR pathway [58]

However, the most visible lifting and firming results gradually appear over 23 months as new collagen forms

Administration method depends on experimental design

TB-500: 16132341 Half-Life : BPC-157: ~4 6 hours

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