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Chronic nicotine consumption profoundly activates macrophages via nAChRs to express pro-inflammatory cytokines, aggravating atherosclerosis and aortic lesions [279]

Reforms would boost safe access for consumers/growers while creating opportunities for cannabis seed buyers in legal markets

It is most common among natives

The prohibition on e-cigarettes was formally added to Palau's Tobacco Control Act through legislative amendments

The results of these analyses are summarized in Supplementary file Figure 4

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