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The primary factor of this condition is insufficient blood circulation in your wrists due to constricted tissues in the joint

This context is everything

Naylor, we are here to discuss cigarettes -- not planes, not cars -- cigarettes

This includes fine dust, pollen, mould spores, pet dander, cooking odours, cigarette smoke, traffic pollution and even toxic gases such as nitrogen dioxide and other volatile compounds produced by household activities and poorly-maintained gas appliances

Stimulants, on the other hand, have the opposite effect