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Treatment of Endometriosis and Leiomyoma with the Association of Miodesin and Gestrinone in Pentravan Through the Vaginal Route

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reported that ectopic endometriotic implants show reduced expression of key mitophagy proteins, including BNIP3, AMBRA1, and Parkin, which further confirms that mitophagy is suppressed in EESCs (59)

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However, results are limited by the small size, short duration, and lack of long-term follow-up [1][60]

Selinexor was not mutagenic in vitro in a bacterial reverse mutation (Ames) assay and was not clastogenic in either the in vitro cytogenetic assay in human lymphocytes or in the in vivo rat micronucleus assay