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In Keap1 knockdown ( Keap1 KD ) mice, the Keap1 mRNA level is reduced to approximately 5% of that in wild-type mice, and constitutive Nrf2 activation is observed in various tissues, such as liver, lung, and kidney

The levels of aglycones produced in our body are known to be affected by multiple factors, and the occurrence of acute hemolytic anemia in G6PD-deficient patients is reported to be dose-dependent ( The severity of favism was compared between three distinct G6PD-deficient variants in the Palestinian Gaza community (38)

doi: 10.1038/nature12820, 62

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Detoxification Aids in the detoxification process by binding to heavy metals and toxins, making them water-soluble for easier excretion

[DOI] [PubMed] [Google Scholar] 59.Zaidi NF, Lagenaur CF, Abramson JJ, Pessah I, Salama G