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However, a study funded by the National Institute on Drug Abuse found that even heavy marijuana smokers did not have an increased risk of developing lung cancer: We hypothesized that there would be a positive association between marijuana use and lung cancer, and that the association would be more positive with heavier use

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As mentioned, the activation of the inflammasome triggers the production of IL-33, an IL-1 family member that was recently discovered to interact with the orphan receptor ST2, preferentially expressed on Th2 cells and mast cells

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Furthermore, all the authors of the manuscript also thank and acknowledge their respective Universities and Institutes