however, evidence is emerging that increased cellular GSSG accumulation may be of equal, if not greater, importance in regulating oxidative stress-triggered detrimental effects
The peptide seems to stimulate the production of nitric oxide, which enhances blood flow and reduces certain forms of inflammation, but it also generates free radicals that damage DNA and proteins
J Physiol Pharmacol 61(2):241250 Ilic S, Drmic D, Franjic S et al (2011a) Pentadecapeptide BPC 157 and its effects on a NSAID toxicity model: diclofenac-induced gastrointestinal, liver, and encephalopathy lesions
Too little may show no visible results, while excessive or unsupervised use can increase the risk of side effects
Biochemistry 38(42):1378713794 Dekker LV, Parker PJ (1997) Regulated binding of the protein kinase C substrate GAP-43 to the V0/C2 region of protein kinase C-delta
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