Concurrently, the transcription factor FoxA2 is both necessary and sufficient for floor plate development, directing floor plate neural progenitors toward a DA fate and playing a pivotal role in DA phenotype induction (Hegarty et al., 2013
Langenberg, C., Hingorani, A
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However, their widespread use has revealed a high incidence of gastrointestinal adverse events, particularly dyspepsia and gastroparesis-like symptoms
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