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The NCFT's controlled micro-trauma also promotes skin renewal alongside the exosomes' melanocyte-modulating effect

Excessive ROS may change the mitochondrial membrane potential (MMP) by regulating the ratio of pro-/anti-apoptosis factors, which leads to the release of Cyt c from the mitochondria into the cytosol (Tripathi et al., 2013

Cell 187 , 23752392.e33 (2024)

The catch is the muscle

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Upon ligand binding, GLP-1R activation enhances glucose-dependent insulin secretion, suppresses glucagon release, delays gastric emptying, and reduces appetite, collectively improving glycemic control and promoting clinically meaningful weight reduction [19]