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They work through complementary but different mechanisms

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elegans protein that plays a similar sequestration role, but functions independent of ubiquitin binding, is MOAG-4 (modifier of aggregation 4) which is homologous to human SERF1 (van Ham et al., 2010)

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People with conditions linked to excessive histamine production, such as arthritis and chronic allergies, may benefit from methionine supplementation