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Early stages are often painless Symptoms may be mistaken for minor mouth issues Lack of regular dental checkups delays detection People tend to ignore persistent changes This delay can allow the disease to progress to more advanced stages

Cigarette smoke exacerbates mouse allergic asthma through Smad proteins expressed in mast cells

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Al MA, Mamun et al (2014) OP14 National profile of non-communicable disease risk factors in Bangladesh