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445,446 A reduction of NAD + levels in cells is observed in many tissues with obesity, like the skeletal muscles, hypothalamus, liver and adipose tissue
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Comparative effectiveness of glucagon-like peptide-1 agonists, dipeptidyl peptidase-4 inhibitors, and sulfonylureas on the risk of dementia in older individuals with type 2 diabetes in Sweden: an emulated trial study Tang, Bowen et al
Possemato R, Marks KM, Shaul YD, Pacold ME, Kim D, Birsoy K, Sethumadhavan S, Woo HK, Jang HG, Jha AK, et al
doi: 10.2337/db06-1454