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However, we note that, as discussed in section III.A.2.a of this proposed rule, CMS already has a policy in place for multiple source drugs for which the absence of ASP data would result in a significant change (that is, a 10 percent or greater change) in the ASP payment limit compared to the payment limit of the previous quarter, as finalized in the CY 2011 PFS final rule (75 FR 73461 through 73465)

Use of NRT is associated with development of oral disorders, although it is rarely published

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Such a shift would increase production costs for corn, wheat, soy, and wheat by almost $2 billion

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