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The tolerogenic mechanism is elegant: by presenting histone epitopes in a context that promotes regulatory rather than effector T cell responses, these peptides essentially re-educate the immune system to tolerate its own nuclear components
A typical titration might start at 0.5 mg per week, increase to 2 mg, and eventually reach doses of 8 mg or 12 mg depending on your providers recommendation
Furthermore, NaBPC157 was administered in the form of a pre-treatment or once daily for 14 days after a capsaicin injection
DOI Park JR, Lee H, Kim SI, Yang SR
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