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When stored properly in the refrigerator at 2 to 8 degrees Celsius, reconstituted semaglutide in bacteriostatic water remains stable for 28 days

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If it still does not dissolve after 5 minutes, the powder may have been exposed to extreme temperatures during shipping or storage, denaturing the peptide

Semaglutide concentrations between 1mg/mL and 5mg/mL are standard, which falls in the mid-range for peptide reconstitution

Any changes in color, the presence of particles, or cloudiness indicate that the medication may have degraded and should not be used

Last reviewed: May 14, 2026 Last updated: May 14, 2026 Written by: Jay Hastings , CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations