GLP-1 based anti-diabetic therapies may be divided into two main groups: GLP-1 agonists and DPP-4 inhibitors (Figure 3)
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Early clinical experiments showed that a continuous intravenous infusion of native GLP-1 could nearly normalize blood glucose levels in people with type 2 diabetes ( [41] ) ( [39] )
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They stressed that the findings are observational at this stage we cant say for certain from these data that the use of GLP-1RAs alone was directly responsible for any of the health outcomes
17 studies were initially identified, but 10 studies were excluded due to lacking or unusable data