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Compared to placebo, the treatment with intramuscular acetyl-l-carnitine significantly reduced weekly mean pain on the VAS, whilst during the open-label part of the study, oral acetyl-l-carnitine improved symptoms in the entire cohort, with no safety issues [81] (Table 2)

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This exposure was routinely conducted every two months, and results were monitored for 180 days

None of them were depressed, but each was saying things like, Well, whats the point? Maybe I dont even care about that job promotion. I dont know what it is, but Im not even excited to go out with my friends. And these three in particular had been on GLP-1s