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Additionally, IL-8 mediates the migration and survival of neural stem cells and oligodendrocyte progenitor cells early in life, and elevated CSF cytokines IL-1 and IL-6 suggest the possibility of microglial activation (199201)

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Following Matrigel polymerization for 10 min at 37 C, advanced DMEM/F12 was supplemented with penicillin/streptomycin, 2 mM GlutaMAX, 10 mM HEPES, 1 B27, 1 N2 (Life Technologies), 1mM N-acetylcysteine (Sigma), and 10 nM gastrin I (Biogems)