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Frias JP, Nauck MA, Van J et al (2018) Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: a randomised, placebo-controlled and active comparator-controlled phase 2 trial

In a broader T2DM population, the REWIND trial demonstrated a significant reduction in MACE, primarily driven by fewer nonfatal strokes [18]

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The mitochondria have a membrane around them, and to be oxidized, the glucose or fatty acids have to get through the membrane into the mitochondria

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