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It still stood at 371,000 by early 1966 after a steady fall during 1965, but by March 1967 it stood at 631,000

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Ten years after the centers launch, Lindblom and others say they underestimated the obstacles that would crowd FDAs path, including industry lawsuits, lobbying and the grinding pace of government bureaucracy

"He was watching these mice and he said, 'You know what, they don't eat as much as the mice that didn't get this medication,' " she says