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Insect cell expression Human GLP1R, human DNGs and human G1-2 constructs were co-expressed in Tni insect cells using baculovirus expression system as previously described(Liang, Khoshouei, Glukhova, et al

Individuals may experience weight regain after discontinuing weight-loss medications, but sustaining a healthier weight can often be achieved through ongoing healthy eating habits and regular exercise

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Internalization and -arrestin recruitment assays were performed by Eurofins Discovery (Fremont, CA, USA)