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The Framework Convention on Tobacco Control (FCTC) of the World Health Organization (WHO) reached a unanimous consensus on regulating ads, promotion, and sponsorship of ECs in 2014, as their safety and efficacy cannot be definitively confirmed, and because they induce addiction similar to that caused by nicotine in cigarettes 10

This was a custom software program that could use survey data about smokers and historical sales data from the tobacco manufacturers, wholesalers and retailers to produce estimates of supply, demand and tax evasion

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According to SUCRA and P-score, dual use ranked highest for stroke risk (SUCRA=0.92 and P-score=0.93), followed by cigarette use (SUCRA=0.77 and P-score=0.76), e-cigarette use (SUCRA=0.45 and P-score=0.45), and former cigarette smoking (SUCRA=0.28 and P-score=0.29)

For example, the researchers said, e-cigarettes include some of the same carbonyl compounds and toxic metals that are known to be carcinogenic and are also found in conventional cigarettes

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