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4 Limitations and implications This narrative review has several limitations

Leach M et al

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Although cells benefit from low or moderate ROS levels, high ROS impose irreversible oxidative damage and so efficient ROS removal is necessary to maintain homeostasis 21,106 and controlled cellular activation

While oral semaglutide offers needle-free convenience, injectable once-weekly semaglutide provides more predictable pharmacokinetics, does not require fasting, and achieves comparable clinical outcomes