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Some of the findings include the following: In a 2022 trial, subjects taking 1,000mg of urolithin A exhibited clinically meaningful improvements in their aerobic endurance and physical performance when compared to subjects who took either 500mg or a placebo.5 A separate 2022 trial examined the effects of 1,000mg urolithin A versus placebo in older adults after four months of daily supplementation

One study noted a potential increased risk of kidney cancer in people taking the drugs

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At doses between about 250 and 1,000 milligrams per day for NMN, and up to around 2,000 milligrams per day for NR, studies show blood NAD+ can rise by 40 to 90 percent or more

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But if you're maybe on the borderline or you just want to try and do something to help yourself to start with, there are a few things that can help: One of the main ways to boost your vitamin B12 intake is through your diet