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For exploratory analysis of factors associated with the treatment response, we used a series of simple linear regressions to examine the association between various baseline covariates and the change in HbA1c level or body weight at 24 weeks

Withdrawal rates due to adverse effects serve as a practical measure of real-world tolerability, making this finding especially relevant for clinical application

doi:10.1016/j.immuni.2012.06.020

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