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2 Materials and methods 2.1 Materials 2.1.1 Animals and feed Twenty SPF male Kunming mice, weighing 1822 g, aged 4 weeks, were purchased from Hunan Slix Laboratory Co., LTD., the certificate number of laboratory animal quality: ZS-202106150014

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The patients weight, height, and latest hematocrit were entered into the Amicus to calculate the amount of plasma to be removed and the amount of 5% albumin to receive

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The volume of each weekly dose depends on the experimental protocol and concentration of the reconstituted solution

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