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Ensure adequate protein intake: Aim for 1.2 to 1.6g of protein per kilogram of body weight daily to preserve lean muscle mass during weight loss

As a rule, too few cells are more sensitive, while too many may mask potential toxicity

The deciding factors are usually clinical intensity and transparency

The minimum four-week interval between dose increases allows adequate time for assessment of both efficacy and tolerability at each dose level

[DOI] [PubMed] Dabke K, Hendrick G, Devkota S

Weight reduction is undoubtedly essential for improving the outcomes for people with obesity and type 2 diabetes mellitus (T2DM) [1]