Vivarelli, S., Spatari, G., Costa, C., Giamb, F
You should contact your GP or healthcare professional urgently if you experience any of the following: Persistent rapid heart rate (tachycardia) at rest, particularly if your resting heart rate exceeds 100 beats per minute consistently Palpitations accompanied by chest pain, shortness of breath, or dizziness , which could indicate a more serious cardiac condition Irregular heartbeat or sensation of skipped beats , especially if this is new or persistent Syncope (fainting) or pre-syncope (feeling like you might faint), which may suggest significant hypotension or cardiac arrhythmia Chest discomfort or pressure , particularly if associated with exertion, sweating, or radiation to the arm or jaw Seek immediate emergency care (call 999) if you experience severe chest pain, difficulty breathing, or symptoms suggestive of a heart attack or stroke
Collectively, these findings reinforced the role of MC4R in metabolism while diminishing confidence in MC3R agonism as a viable pathway for weight loss
They can determine whether this side effect is attributed to semaglutide or something else
These include: Nausea (most common, particularly at higher doses) Vomiting Diarrhoea Constipation Decreased appetite Gastrointestinal events were generally mild to moderate in severity and tended to resolve as participants adapted to each dose level
[ 10 points] 1
