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Children generally require weight-adjusted regimens, often 100 mcg monthly after initial loading

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P = .002)

muciniphila and Lactobacillus plantarum jointly remodel immunity by reducing IL-17/IL-6, elevating IL-10, inhibiting Th17 differentiation, and restoring claudin-7 polarity, while promoting Roseburia proliferation and TCA cycle activation to enhance immunometabolic crosstalk [117]