These concerns first gained prominence around 20112013, when regulatory agencies began investigating potential pancreatic safety signals associated with incretin-based therapies, including both GLP-1 receptor agonists and DPP-4 inhibitors
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GLP-1 drugs are primarily recommended for: Adults with type 2 diabetes who arent seeing results from oral medications and need better blood sugar control People with obesity or with a BMI over 30 (with or without diabetes) seeking medical weight management Doctors may also consider GLP-1 RAs for patients with cardiovascular risk factors, as some of these drugs have shown heart-protective benefits
Fallon MD, Perry HM, 3rd, Bergfeld M, Droke D, Teitelbaum SL, Avioli LV
