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Reactive oxygen species generated by NADPH oxidase are involved in neurodegeneration in the pilocarpine model of temporal lobe epilepsy

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Some specific causes include: Certain medical conditions

Gamma-glutamylcyclotransferase promotes the growth of human glioma cells by activating Notch-Akt signaling

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On the other hand, in rice noe1 mutant, in the absence of OsNOE1/OsCATC function, the accumulation of H 2 O 2 induces NO production through elevating nitrate reductase expression, which is further integral to H 2 O 2 induced leaf cell death through S -nitrosylation of GAPDH and thioredoxin (Wang et al., 2013)