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Compared with SGLT-2 inhibitors, the GLP-1 receptor agonist-SGLT-2 inhibitor combination was associated with a 29% lower risk of major adverse cardiovascular events (7.6 v 10.7 events per 1000 person years

Bile acids trigger GLP-1 release predominantly by accessing basolaterally located G proteincoupled bile acid receptors. Endocrinology 156.11 (2015): 3961-3970

By acting on GLP-1 receptors in the brain and pancreas, it contributes to reducing hunger and maintaining a normal blood glucose level

This may help reduce side effects such as nausea and fatigue, especially during the first weeks of treatment

Many people eat not because theyre hungry, but because theyre bored, stressed, or celebrating

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