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Phase 3 TRIUMPH-4 (NCT05931367) reported 28.7% body weight loss at 12 mg, 26.4% at 9 mg, vs 2.1% placebo at 68 weeks

However, many peptides currently being discussed in wellness and longevity medicine are not FDA-approved for the uses commonly promoted in those settings

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GHRP-2 offers slightly cleaner release with less appetite stimulation

Hormonal Balance: Supports overall hormonal health

1.4 Orexins and GHRH In addition to regulating GH secretion and metabolic status, growth GHRH plays a role in promoting non-rapid eye movement (non-REM) sleep across various species through a mechanism independent of GH action [45]