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Supporting this concept, mitochondrial dysfunction in circulating PBMCs features enhanced immunomodulation in patients with advanced acute-chronic liver diseases [110, 111]

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et al., The New England Journal of Medicine , 2023, 10.1056/NEJMoa2301972 Study Objective To evaluate the efficacy, safety, and dose-response effect of Retatrutide a triple GIP, GLP-1, and glucagon receptor agonist in adults with overweight and obesity

Demeneix, B., Vandenberg, L