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Enhanced blood sugar control in type 2 diabetes, via both incretin pathways

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It is the second-leading cause of optic nerve blindness, following glaucoma, and the most common cause of sudden optic nerve blindness

Most patients with type 2 diabetes are overweight or obese

Mechanically, ARID1A is a component of the SWI/SNF complex, which binds to the SLC7A11 promoter and promotes NRF2-mediated SLC7A11 transcriptional activation

A previous history of vitiligo can also make a patient more vulnerable to a drug-induced extension of their pigment loss