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Refrigeration Unlike some medications that require strict refrigeration, vitamin B12 injections come in different formulations, and their storage requirements vary: Cyanocobalamin Injections: Many cyanocobalamin B12 injections can be stored at room temperature (68F to 77F / 20C to 25C) and should be kept away from direct light

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Methylcobalamin, vitamin B12 preparations containing benzyl alcohol should be avoided in premature neonates because benzyl alcohol has been associated with gasping syndrome, a potentially fatal condition characterized by metabolic acidosis and CNS, respiratory, circulatory, and renal dysfunction