Journal of Endocrinology & Metabolism
When you take a standard capsule or tablet, it must pass through the stomach
Kaneto H et al (2021): Multifaceted Mechanisms of Action of Metformin Which Have Been Unraveled One after Another in the Long History
For 5-Amino-1MQ, the evidence base is considerably more limited
Briefly, 100 age-matched male and female flies were segregated in separate vials and transferred to fresh vials during the experimental period every five days
Deleterious off-target effects in women 10 years or more past menopause, such as ovarian, endometrial, and breast cancers, intravascular thrombosis, cardiovascular episodes, and stroke, and suppression of endogenous testosterone and libido and increased risk of prostate cancer in men, have precluded broad clinical applications (Hall and Phillips, 2005