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Initiation rates for AOM GLP-1 RA are about the same in September 2025, relative to June 2025 (+1.5%)
However, cagrilintide and tirzepatide work through entirely different receptor systems
Low levels have been linked with symptoms such as low mood, increased anxiety, irritability, and mood swings
Calcium supplements (especially when taken without food), high-dose vitamin C (which converts to oxalate), and topiramate (not licensed for weight loss in the UK) all increase stone risk
Agarwal S, Rao AV
Lack of pigmentation in suspect pedal lesions can compound the problem
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