Cell 142 , 375386 (2010)
Endogenous Roles The compound performs three main functions: neutralizing reactive oxygen species, conjugating xenobiotics for Phase II detoxification (via glutathione S-transferases), and recycling other antioxidants such as vitamins C and E
Factors like strength, dosage, method of administration, and other aspects may vary, making a direct comparison between the effects and risk profiles of FDA-approved medications and compounded medications challenging
FDA found no adequate clinical program that could define common adverse effects, rare serious effects, dose relationships, medication interactions, or risks in vulnerable patient groups
When administered according to clinical guidelines, epithalon presents relatively few and minor potential side effects that cease after discontinuation of treatment
In contrast, s.c