Pharmacologically this yields a highly selective GHS-R1a agonist which, in classical rodent studies (Raun et al., Eur J Endocrinol 1998), does not significantly elevate cortisolemia, ACTH, prolactin or FSH/LH at effective doses, unlike GHRP-2 and GHRP-6
Research categories and tags for this page include Combo, GHRH, GHRP, Growth Hormone
What the clinical evidence shows The landmark Phase 2 trial by Teichman et al
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How are peptides given
CJC-1295 + Ipamorelin is a USA-manufactured dual-peptide GH axis research blend combining CJC-1295 No DAC (ModGRF 1-29) a synthetic GHRH analogue that activates the GHRH receptor on anterior pituitary somatotrophs via Gs-cAMP signaling and Ipamorelin, a selective GH secretagogue that activates the ghrelin receptor (GHS-R1a) via the distinct Gq/11 intracellular pathway, providing simultaneous dual-receptor GH axis stimulation in a single research preparation
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