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There is, however, evidence to support considering closer follow-up when initiating a GLP-1 RA, particularly if rapid improvement in glycemic control is anticipated, following a baseline dilated fundus examination performed around the time of therapy initiation

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Individuals with a BMI of 27 or greater who have at least one weight-related health condition, such as high blood pressure or high cholesterol

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Both MT1 and MT2 are contraindicated in subjects who are pregnant, breastfeeding, under 18 years of age, or who have a prior history of skin-related malignancies