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Interestingly, one Smad7 antisense oligonucleotide, mongersen, was recently shown in a double-blind controlled trial to enhance the 15-day remission rate versus placebo in patients with Crohns disease (Monteleone 2015)

First, lets back up and cover a few basics: Short for nicotinamide adenine dinucleotide, NAD is a coenzyme found in every cell of the body

It's formulated to address the biochemical root of why high-achievers can't switch off and to build the kind of nervous system resilience that holds, long term

doi: 10.1124/jpet.119.257576

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