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Phys Ther (2014) 94(12):181625

One line of the research is that mutations arrest or block voltage-dependent channel inactivation resulting in influx

Yes, this is an important marker for sure but there are many others

Due to their high water content, structural similarity to natural tissues, and favorable biocompatibility, hydrogels are widely used in biomedical fields, particularly for drug delivery, facilitating controlled release and enhancing efficacy (198200)

What doesnt take care of itself is protein distribution

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